10s for each image and videos either with specified duration or with 0 (it will auto detect video duration then)
that’s pretty much it, after it’s set it should cycle through all items in the region then start from the first item, after 300s it will reload the layout (as I think that’s the longest duration you have there) and start from the beginning and so on. (unless there is a different layout scheduled as well, if so after this layout will finish player will switch to the next layout).
Understanding Media Duration and how it affects the playback of a Layout